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Scientist (Chemist/Synthesis)

Company: Pharmacyclics
Location: Sunnyvale
Posted on: June 13, 2019

Job Description:

Scientist (Chemist/Synthesis)

Location: Sunnyvale, CA

Pharmacyclics is committed to the development and commercialization of novel therapies intended to improve the quality and duration of life and to resolve serious unmet medical needs for cancer patients. Pharmacyclics is a wholly-owned subsidiary of AbbVie (NYSE:ABBV), a global, research-based biopharmaceutical company. Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products and a pipeline containing multiple promising new molecules that are being studied in more than 200 clinical trials for over 20 different types of cancer.

More than 1,200 Pharmacyclics and AbbVie research scientists, clinicians, marketing, operations and corporate professionals work in the San Francisco Bay Area. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments. Together, we are striving to outsmart cancer.

Title: Scientist (Chemist/Synthesis)

General Position Summary/Purpose:

Work will focus on conducting chemistry research in the lab in the field of cancer-drug discovery and involve the design, synthesis, purification and characterization of biologically-active organic molecules for drug discovery programs.

Key Accountabilities/Core Job Responsibilities:


  • W ill include scale-up of key synthetic intermediates and molecules of interest, selection and strategic development of synthetic routes for molecular scaffolds and analysis of experimental data and quality checks.
  • As required, will be asked to transfer synthetic methodologies and communication to CROs and prepare reports and make presentations of data both internally and externally.
  • Will support process development of drug candidates when necessary.
  • Maintain a detailed scientific notebook, analytical data and other scientific information
  • Perform routine maintenance on laboratory instruments; and maintain clean and safe laboratory.
  • Will collaborate with interdisciplinary teams
  • Perform other duties, as assigned.


    Required:


    • Ph.D. in Chemistry
    • At least 6 months in position offered or in an organic synthesis position
    • Strategic design of synthetic routes and optimization of reaction and purification procedures
    • Compound purification
    • Safe handling of chemical reagents and products
    • Quality analysis
    • Data analysis
    • Preparation of scientific reports and writing-up experimental procedures for patents
    • Hypothesis-driven research
    • Organic methodology
    • Apply scientific literature to address and solve problems in medicinal chemistry research


      Hiring Requirements: Background & Reference Checks

      Equal Opportunity Employer Minorities/Women/Veterans/Disabled

Keywords: Pharmacyclics, Sunnyvale , Scientist (Chemist/Synthesis), Other , Sunnyvale, California

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