Research Scientist - Yurkovich Lab

Company: Buck Institute
Location: Novato
Posted on: May 13, 2025

Job Description:

Location:on-site, Buck campus, Novato, CA
Compensation: $110,000 - $165,000, DOE
Appointment: 18-month position (potential to extend)
Citizenship Requirement: U.S. citizens only

Do you aspire to push the boundaries of computation to catalyze scientific breakthroughs?
Imagine predicting microbial behavior with the same precision used to design circuits. At the Buck Institute, we're building a cutting-edge platform to simulate dynamic bacterial function by combining multi-dimensional microbial data, mechanistic knowledge, and AI. This project will revolutionize biomanufacturing and antimicrobial discovery, transforming them into predictive, designable processes. The implications range from optimizing industrial production to deepening our understanding of biological systems that shape human aging.

We are seeking a highly motivated Research Scientist to join the Yurkovich Lab. The successful candidate will contribute to a project focused on developing and applying a computational simulation platform to predict dynamic bacterial behavior, integrating multi-dimensional microbial state data with mechanistic biological knowledge and AI. This position offers an excellent opportunity to contribute to efforts at the forefront of transforming our understanding of aging by accurately predicting phenotypic function.

If you're ready to drive scientific discovery at the intersection of cutting-edge computation and transformative experimentation to redefine our understanding of aging, we encourage you to apply.

Responsibilities
Computational Leadership

• Design, develop, and maintain software applications and tools for data analysis, modeling, and visualization.
• Collaborate with team members to implement advanced computational models and algorithms.
• Optimize software for performance and scalability in large-scale data processing.
• Ensure data quality, reproducibility, and integrity through best-in-class data management.
• Author and maintain documentation for software applications and tools.
• Stay abreast of new developments in computational biology, software engineering, and AIExperimental Contributions
  • Conduct Minimum Inhibitory Concentration (MIC) assays to evaluate bacterial growth responses.
  • Execute bacterial sample preparation protocols for multi-omic data generation (e.g., transcriptomics, proteomics, metabolomics).Required Qualifications
    • Ph.D. in Bioengineering, Computer Science, Computational Biology, Biological Sciences, or a related field.
    • Demonstrated expertise in microbiology and molecular biology
    • Industry experience in biomanufacturing or antimicrobial resistance (AMR).
    • Proficient in Python for scientific computing and data analysis.
    • Experience with computational modeling of biological systems, including metabolic models (e.g., genome-scale modeling).
    • Strong analytical and data interpretation skills.
    • Proven ability to work both independently and collaboratively in multidisciplinary teams.
    • Excellent written, verbal, and presentation skills.Preferred Qualifications
      • Experience developing and implementing generative AI tools.
      • Hands-on experience with MIC assays, bacterial culture techniques, and omic sample preparation.
      • Familiarity with genome sequencing and assembly of bacterial species.
      • Expertise in integrating multi-omic datasets into computational frameworks.
      • Demonstrated leadership in managing projects or mentoring junior researchers.
      • Prior military or civil service experience is valued.About the Buck Institute for Research on Aging
        Our success will ultimately change healthcare. At the Buck, we aim to end the threat of age-related diseases for this and future generations by bringing together the most capable and passionate scientists from a broad range of disciplines to identify and impede the ways in which we age. Globally recognized as the pioneer and leader in efforts to target aging-the number one risk factor for diseases including Alzheimer's, Parkinson's, cancer, macular degeneration, heart disease, and diabetes-the Buck seeks to help people live better longer. We are an equal opportunity employer.
        
        To Apply
        Please apply online and submit your CV plus a PDF document that includes a summary of your research interests and the names, email, and phone numbers of 3 references.
        
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Keywords: Buck Institute, Sunnyvale , Research Scientist - Yurkovich Lab, Healthcare , Novato, California